Month: November 2024

Home / Month: November 2024

Doggles Sea Life Catnip Cat Toy – Shark

November 24, 2024 | News | No Comments

Cats Love Fish so why not give them a really cute one with the Doggles Sea Life Catnip Cat Toy Shark!

  • Plush shark
  • USA grade catnip
  • Poly-filled with catnip packet

Why We Love It:

Your cat will go crazy for this cute Sea Life Catnip Cat Toy! High-grade, first quality catnip, certified organically grown in the USA. No fillers 100% fresh catnip. Poly fill stuffed with a catnip packet inside. Plush toys. Making cats happy.

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Ducati Performance C3 Leather Gloves

November 24, 2024 | News | No Comments

Performance C3 gloves combine the characteristics of a racing product with those of a garment suitable for road sports use. Made of soft goatskin, they feature carbon knuckles and reinforcements at the points of greatest stress to ensure the highest safety and performance in case of sports use. Furthermore, the soft protections and excellent comfort make them perfect even for frequent use at lower intensity. To complete its versatility and excellent performance, this 100% Ducati accessory is available in two color variants and with a gritty design. Check Legal Notes and Product Information on www.ducati.com.

Features

  • Perforated leather.
  • Adjustable closure wrist strap.

Materials – Outside

  • Goat leather, 0.6/0.8 mm thickness, high fit and riding sensitivity.
  • Suede microfibre reinforcement on the palm.

Protection

  • Shock-absorber padding on the palm, outer side, cuff.
  • Garment CE certified (Reg. EU2016-425).

Care

  • Do not use chlorine bleach.
  • Hand wash only.
  • Do not iron.
  • Do not dry clean.
  • Do not use solvent-based stain removers.
  • Do not tumble dry.
  • VERY IMPORTANT FOR ALL LEATHER TECHNICAL ITEMS: clean with the suitable leather care kit or using a sponge or wet cloth and mild soap – Lightly rub and dry with a clean cloth
  • Do not dry under the sun or near heat sources
  • Do not store item in a cellophane bag

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Premier League side Hull City have in recent hours joined the race to sign Angers striker Nicolas Pépé, according to L’Équipe.

Lille, Lyon, Marseille as well as Hull and notably Liverpool are listed as interested parties.

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The trio of French sides are all said to have had bids of around €6m rejected for the Ivorian international, who is expected home imminently after his side were eliminated from AFCON.

Angers want €10m in order to allow the player to leave.

Marseille have offer accepted for Grégory Sertic

November 22, 2024 | News | No Comments

Marseille have had an offer accepted for Bordeaux’s French central midfielder or defender Grégory Sertic worth €2m, according to Le Parisien.

The player is set to join OM on a four year deal, according to the report, whether that means 4.5 or 3.5 is unclear.

Sertic’s Marseille contract was due to expire with Bordeaux at the end of the current campaign.

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November 22, 2024 | News | No Comments

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DATRON Rocks Milling PVC Guitar Pickguard

November 22, 2024 | News | No Comments

Frank Xydias works in the Department of Engineering running Advanced Manufacturing and Computer Aided Design at Milford High School’s Applied Technology Center in Milford, NH. In this educational setting, the group often accepts “live jobs” acting like a job shop within the community. That was the case when they agreed to do a one-off part in a material they thought would be acrylic. The part was a pick-guard for a Danelectro Wild Thing Baritone electric guitar. But when the material came in they found out that it was in fact, PVC. Ultimately, this would be a milling PVC application.

Milling PVC Electric Guitar Pickguard

Application Technician, Kyle Newman, was assigned to the project and he was immediately confident that the job was a nice fit for DATRON technology. First, flat stock like this is ideally suited to the use of vacuum table workholding which is an option with DATRON machines. Secondly, a wide range of DATRON customers use their machines to mill and engrave engineered plastics including Delrin, Torlon, G10, FR4, Durastone, military-grade acrylic … you name it. So, milling PVC was not going to be an issue. As for the cuts required, there was nothing complex about the part – although Newman did have some concerns about potential delamination (due to the 3-ply construction of the supplied PVC stock) that might impact the edge finish.

CNC Programming and Tools for Milling PVC

The Mastercam file provided by the school didn’t include toolpaths or speeds. So, Newman brought it into Autodesk Inventor and used HSMWorks to create tool paths. A single tool change would be required with the contour cut being done with a standard DATRON 3mm single flute end mill and a smaller 1.5mm single flute would be used to make the mounting holes used to attach the pickguard to the guitar.

CNC Milling Machine Used for Milling PVC

Newman decided to use DATRON’s flagship M8Cube high-speed milling machine featuring a 60,000 RPM 2kW spindle and an integrated vacuum table. This machine also has an integrated probe which was used to map the surface of the PVC sheet to detect any irregularities. Irregularities were automatically compensated for in the software before the milling began.

Machining Strategies for Milling PVC Pickguard

Operation: Contour around profile of guitar, slot and larger through holes.
Tool p/n: 0068430E
Tool Type: 3mm dia. single flute
Width of Cut: 100% (3mm/0.11811″)
@ 25,000 RPM: 118.11 inch/min feed

Operation: Bore milling small mounting holes
Tool p/n: 0068015E
Tool Type: 1.5mm dia. single flute
Width of Cut: 100% (1.5mm/0.0590551″)
@ 25,000 RPM: 118.11 inch/min feed

Results of Milling PVC Pickguard

Regardless of the concerns about the construction of the supplied 3-ply PVC, the end result was perfect including the edge finish on the contour cuts and no delamination occurred. Newman was able to present the part to Frank Xydias who in turn, presented it to a very happy end customer.

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Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin.  Quintana VM, Torres NI, Wachsman MB, Sinko PJ, Castilla V, Chikindas M., J. Appl. Microbiol., 2014, 117, 1253-9.

AIMS:

In this study, we evaluated the antiviral activity of subtilosin, a cyclical peptide isolated from Bacillus amyloliquefaciens, against herpes simplex virus type 2 (HSV-2) in cell cultures and we investigated subtilosin mode of action.

METHODS AND RESULTS:

We determined, using a virus yield inhibition assay, that noncytotoxic concentrations of subtilosin inhibit HSV-2 replication in Vero cell cultures. Subtilosin strongly inhibited extracellular and total virus production even when it was added at 8 h postinfection indicating that not only virus release but also viral particle formation is impeded by the antiviral peptide. Although viral glycoprotein gD level of expression is not affected by the bacteriocin, an altered pattern of gD intracellular localization was detected by immunofluorescence assay in subtilosin-treated culture. On the other hand, at high concentrations, subtilosin displays virucidal action.

CONCLUSIONS:

Subtilosin displays antiviral and virucidal actions against HSV-2. The target of subtilosin inhibitory effect would be late stages of the viral replicative cycle such as viral glycoprotein intracellular transport.

SIGNIFICANCE AND IMPACT OF THE STUDY:

Given its antimicrobial activity and its safety for human tissues, subtilosin could represent a valuable alternative to be considered in the development of new microbicide formulations.

© 2014 The Society for Applied Microbiology.

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Dainese Unruly Ergo-Tek Ladies Gloves

November 22, 2024 | News | No Comments

 

Unruly Woman Ergo-Tek Gloves are certified fabric motorcycle gloves with soft sheepskin reinforcements.

Designed specifically by following female ergonomics, they’re extremely comfortable and elastic due to the seamless knit fabric construction of the back, while ensuring the highest levels of protection due to knuckles with Ergo-Tek technology.

The mesh fabric inserts make the gloves light and ventilated, perfect for wearing even in the hottest climates, while the Smart Touch system allows you to use touch screens without taking the gloves off, making them even more practical and functional.

 

CHARACTERISTICS:

  • Dainese Smart Touch
  • Knit back construction
  • Reflective inserts

 

ERGONOMICS:

  • Adjustable cuff strap
  • Neoprene cuff
  • Pre-curved fingers

 

MAIN MATERIALS:

  • Leather palm reinforcement
  • Micro suede palm

 

PERFORMANCE SHOCK:

  • Ergo-Tek knuckles
  • Gloves certified to CE – Cat. II – EN 13594/2015 Standard cat. II lev. 1

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